A Clinical Trial Of Vena Caval Filters In The Prevention Of Pulmonary Embolism In Patients With Proximal Deep-Vein Thrombosis
Intervention
Vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis
Patient population
400 patients with proximal deep-vein thrombosis who were at risk for pulmonary embolism to receive a vena caval filter (200 patients) or no filter (200 patients)
Conclusion
In high-risk patients with proximal deep-vein thrombosis, the initial beneficial effect of vena caval filters for the prevention of pulmonary embolism was counterbalanced by an excess of recurrent deep-vein thrombosis, without any difference in mortality. Our data also confirmed that low-molecular-weight heparin was as effective and safe as unfractionated heparin for the prevention of pulmonary embolism
This blinded trial did not show a significant reduction of systolic blood pressure in patients with resistant hypertension 6 months after renal-artery denervation as compared with a sham control.